EPHA5, EPH receptor A5

EPHA5, EPH receptor A5

• This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Aug 2013]

• Gene Synonyms (CEK7, EHK-1, EHK1, EK7, HEK7, TYRO4, ephrin type-A receptor 5, EPH homology kinase 1, EPH-like kinase 7, brain-specific kinase, epididymis secretory sperm binding protein, receptor protein-tyrosine kinase HEK7, tyrosine-protein kinase receptor EHK-1,)
• NCBI Gene ID: 2044
• Species: Homo sapiens (Human)
• UNIPROT ID#>>F8W9W0
  UNIPROT ID#>>Q59FT4
  UNIPROT ID#>>P54756
  UNIPROT ID#>>B7ZKJ3
  UNIPROT ID#>>B7ZKW7
  UNIPROT ID#>>F8VP57
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

EPH receptor A5 interacts with:

• dual specificity phosphatase 21
  erb-b2 receptor tyrosine kinase 2
  NEDD4 E3 ubiquitin protein ligase
  signal transducer and activator of transcription 3
  tetraspanin 3
  TNF receptor associated factor 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.