FOXL1, forkhead box L1

FOXL1, forkhead box L1

• This gene encodes a member of the forkhead/winged helix-box (FOX) family of transcription factors. FOX transcription factors are characterized by a distinct DNA-binding forkhead domain and play critical roles in the regulation of multiple processes including metabolism, cell proliferation and gene expression during ontogenesis. [provided by RefSeq, Nov 2012]

• Gene Synonyms (FKH6, FKHL11, FREAC7, forkhead box protein L1, forkhead-like 11, forkhead-related protein FKHL11, forkhead-related transcription factor 7,)
• NCBI Gene ID: 2300
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q12952
  UNIPROT ID#>>Q498Y4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

forkhead box L1 interacts with:

• alanyl-tRNA synthetase 2, mitochondrial
  aspartyl-tRNA synthetase 2, mitochondrial
  ATP binding cassette subfamily F member 3
  AT-rich interaction domain 3B
  bromodomain adjacent to zinc finger domain 1A
  B-TFIID TATA-box binding protein associated factor 1
  chromodomain helicase DNA binding protein 1 like
  cleavage and polyadenylation specific factor 2
  component of oligomeric golgi complex 5
  cytoskeleton associated protein 5
  defective in cullin neddylation 1 domain containing 5
  DExD-box helicase 39A
  DExD-box helicase 52
  DNA polymerase epsilon, catalytic subunit
  DNA topoisomerase III beta
  Ecm29 proteasome adaptor and scaffold
  extended synaptotagmin 1
  GADD45G interacting protein 1
  general transcription factor IIIC subunit 1
  general transcription factor IIIC subunit 4
  general transcription factor IIIC subunit 5
  golgi brefeldin A resistant guanine nucleotide exchange factor 1
  GTPase activating protein and VPS9 domains 1
  HEAT repeat containing 1
  heat shock protein family A (Hsp70) member 14
  HECT and RLD domain containing E3 ubiquitin protein ligase 5
  helicase, lymphoid specific
  heterogeneous nuclear ribonucleoprotein U like 2
  hexokinase 2
  hexokinase 3
  histone deacetylase 2
  histone deacetylase 6
  integrator complex subunit 3
  interferon regulatory factor 9
  interferon related developmental regulator 1
  isoleucyl-tRNA synthetase 1
  kinesin family member 22
  lamin B2
  MAP7 domain containing 1
  midasin AAA ATPase 1
  mitochondrial ribosomal protein L38
  mitochondrial ribosomal protein L45
  mitochondrial ribosomal protein S30
  mitogen-activated protein kinase kinase 3
  myosin IXB
  NAD(P) dependent steroid dehydrogenase-like
  N-alpha-acetyltransferase 40, NatD catalytic subunit
  negative elongation factor complex member C/D
  N-ethylmaleimide sensitive factor, vesicle fusing ATPase
  NOC2 like nucleolar associated transcriptional repressor
  non-SMC condensin I complex subunit D2
  non-SMC condensin I complex subunit G
  non-SMC condensin I complex subunit H
  non-SMC condensin II complex subunit D3
  NOP9 nucleolar protein
  NOVA alternative splicing regulator 1
  nuclear envelope integral membrane protein 1
  nuclear receptor subfamily 2 group C member 2
  nuclear receptor subfamily 2 group F member 1
  nuclear receptor subfamily 3 group C member 1
  nuclear transcription factor, X-box binding like 1
  nucleolar protein 9
  nucleoporin 107
  nucleoporin 133
  nucleoporin 205
  nucleoporin 98 and 96 precursor
  origin recognition complex subunit 2
  origin recognition complex subunit 3
  origin recognition complex subunit 4
  PDS5 cohesin associated factor A
  phosphatidylinositol 4-kinase alpha
  poly(U) binding splicing factor 60
  proliferation-associated 2G4
  protein phosphatase 6 regulatory subunit 1
  RAD50 double strand break repair protein
  RAD50 interactor 1
  RALY heterogeneous nuclear ribonucleoprotein
  RAN binding protein 2
  Ran GTPase activating protein 1
  regulator of microtubule dynamics 3
  replication timing regulatory factor 1
  ribosome binding protein 1
  SATB homeobox 1
  SATB homeobox 2
  scaffold protein involved in DNA repair
  scribble planar cell polarity protein
  SIX homeobox 5
  sorting nexin 2
  spermatid perinuclear RNA binding protein
  sphingomyelin phosphodiesterase 4
  splicing factor 3b subunit 1
  stromal antigen 1
  structural maintenance of chromosomes 1A
  structural maintenance of chromosomes 2
  structural maintenance of chromosomes 3
  structural maintenance of chromosomes 4
  SURP and G-patch domain containing 2
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
  SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
  symplekin
  TATA-box binding protein associated factor 9
  TLE family member 3, transcriptional corepressor
  translocase of outer mitochondrial membrane 40
  translocase of outer mitochondrial membrane 70
  tRNA methyltransferase 2 homolog A
  tyrosyl-tRNA synthetase 1
  ubiquitination factor E4A
  UFM1 specific ligase 1
  UTP20 small subunit processome component
  UTP6 small subunit processome component
  valyl-tRNA synthetase 1
  YY1 transcription factor
  zinc finger homeobox 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.