ADGRL3, adhesion G protein-coupled receptor L3

ADGRL3, adhesion G protein-coupled receptor L3

• This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CIRL3, CL3, LEC3, LPHN3, adhesion G protein-coupled receptor L3, CIRL-3, calcium-independent alpha-latrotoxin receptor 3, latrophilin homolog 3 (cow), latrophilin-3, lectomedin 3,)
• NCBI Gene ID: 23284
• Species: Homo sapiens (Human)
• UNIPROT ID#>>E7EUW2
  UNIPROT ID#>>E7EVD6
  UNIPROT ID#>>Q9HAR2
  UNIPROT ID#>>E7ESV6
  UNIPROT ID#>>B7Z2G2
  UNIPROT ID#>>E7EUP0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

adhesion G protein-coupled receptor L3 interacts with:

• C-type lectin domain family 2 member D
  fibronectin leucine rich transmembrane protein 1
  inositol-pentakisphosphate 2-kinase
  matrix metallopeptidase 26

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.