Skip Navigation Links Home » Resources » Gene Detail

Nr0b2, nuclear receptor subfamily 0, group B, member 2

Matching ORF Clones

    No catalog ORF clones available (link to the custom ORF request form)

Request a Custom Clone

Don't see what you need?

Request My Custom Clone »
  • Gene Overview
  • Interaction Network
  • Sequence Verification

Nr0b2, nuclear receptor subfamily 0, group B, member 2

  • This gene encodes a member of the nuclear hormone receptor family of proteins. The encoded orphan receptor lacks a DNA binding domain but modulates gene expression by interacting with other hormone receptors to competitively inhibit binding of coactivators while also acting as a transcriptional corepressor. The encoded receptor may regulate bile acid synthesis and sexual maturation in males. Homozygous knockout mice exhibit accumulation of bile acids, reduced levels of low density lipoprotein cholesterol (LDL-C), and in male mice, earlier testicular maturation. [provided by RefSeq, Aug 2015]

  • (No alternate names found)
  • NCBI Gene ID: 23957
  • Species: Mus musculus (Mouse)
  • UNIPROT ID#>>Q62227
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nuclear receptor subfamily 0, group B, member 2 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

It appears that you have Javascript disabled. Our website requires Javascript to function correctly. For the best browsing experience, please enable Javascript.