FRG1, FSHD region gene 1

FRG1, FSHD region gene 1

• This gene maps to a location 100 kb centromeric of the repeat units on chromosome 4q35 which are deleted in facioscapulohumeral muscular dystrophy (FSHD). It is evolutionarily conserved and has related sequences on multiple human chromosomes but DNA sequence analysis did not reveal any homology to known genes. In vivo studies demonstrate the encoded protein is localized to the nucleolus. [provided by RefSeq, Jul 2008]

• Gene Synonyms (FRG1A, FSG1, protein FRG1, FSHD region gene 1 protein, facioscapulohumeral muscular dystrophy region gene-1,)
• NCBI Gene ID: 2483
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14331
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

FSHD region gene 1 interacts with:

• cullin associated and neddylation dissociated 1
  CWC22 spliceosome associated protein homolog
  elongation factor Tu GTP binding domain containing 2
  exosome component 8
  glycine N-methyltransferase
  H2B clustered histone 8
  H3 clustered histone 1
  H4 clustered histone 1
  HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
  hes related family bHLH transcription factor with YRPW motif 1
  keratin 40
  kinase suppressor of ras 1
  La ribonucleoprotein 7, transcriptional regulator
  leucine zipper tumor suppressor 2
  methylphosphate capping enzyme
  nuclear receptor subfamily 2 group C member 2
  pleckstrin homology domain containing A4
  RNA binding protein, mRNA processing factor
  small nuclear ribonucleoprotein U1 subunit 70
  spliceosome associated factor 3, U4/U6 recycling protein
  ubiquitin conjugating enzyme E2 O

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.