- Gene Overview
- Interaction Network
- Sequence Verification
POU2F3, POU class 2 homeobox 3
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This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
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Gene Synonyms (POU domain, class 2, transcription factor 3, POU domain transcription factor OCT11a, octamer-binding protein 11, octamer-binding transcription factor 11, transcription factor PLA-1, transcription factor Skn-1, Epoc-1, OCT-11, OCT11, OTF-11, PLA-1, PLA1, Skn-1a,)
- NCBI Gene ID:
25833
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q9UKI9
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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POU class 2 homeobox 3 interacts with:
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