CHRDL2, chordin like 2

CHRDL2, chordin like 2

• This gene encodes a member of the chordin family of proteins. Chordin family members are secreted proteins that share a cysteine-rich pro-collagen repeat domain and associate with members of the transforming growth factor beta superfamily. In vitro assays demonstrate a direct interaction between the encoded protein and human activin A. This gene is expressed in many tissues including osteoblasts, where it is differentially expressed during differentiation. In addition, its expression is upregulated in human osteoarthritic joint cartilage, suggesting a role in adult cartilage regeneration. [provided by RefSeq, Jan 2015]

• Gene Synonyms (chordin-like protein 2, breast tumor novel factor 1, chordin-related protein 2, BNF1, CHL2,)
• NCBI Gene ID: 25884
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6WN34
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

chordin like 2 interacts with:

• BTG3 associated nuclear protein
  enkurin domain containing 1
  family with sequence similarity 90 member A1
  G protein signaling modulator 3
  zinc finger protein 417
  zinc finger protein 587

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.