DHDH, dihydrodiol dehydrogenase

DHDH, dihydrodiol dehydrogenase

• This gene encodes an enzyme that belongs to the family of dihydrodiol dehydrogenases, which exist in multiple forms in mammalian tissues and are involved in the metabolism of xenobiotics and sugars. These enzymes catalyze the NADP1-linked oxidation of transdihydrodiols of aromatic hydrocarbons to corresponding catechols. This enzyme is a dimeric dihydrodiol dehydrogenase, and it differs from monomeric dihydrodiol dehydrogenases in its high substrate specificity for trans-dihydrodiols of aromatic hydrocarbons in the oxidative direction. [provided by RefSeq, Jul 2008]

• Gene Synonyms (trans-1,2-dihydrobenzene-1,2-diol dehydrogenase, 3-deoxyglucosone reductase, D-xylose 1-dehydrogenase, D-xylose-NADP dehydrogenase, dihydrodiol dehydrogenase (dimeric), 2DD, HUM2DD,)
• NCBI Gene ID: 27294
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UQ10
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

dihydrodiol dehydrogenase interacts with:

• coiled-coil domain containing 12

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.