GPR21, G protein-coupled receptor 21

GPR21, G protein-coupled receptor 21

• This gene encodes a member of the G-protein-coupled receptor 1 family. G-protein coupled receptors are membrane proteins which activate signaling cascades as a response to extracellular stress. The encoded protein activates a Gq signal transduction pathway which mobilizes calcium. [provided by RefSeq, Nov 2012]

• Gene Synonyms (probable G-protein coupled receptor 21,)
• NCBI Gene ID: 2844
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DSD1
  UNIPROT ID#>>Q99679
  UNIPROT ID#>>H9NIL4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

G protein-coupled receptor 21 interacts with:

• adhesion G protein-coupled receptor L1
  anoctamin 6
  ATP synthase membrane subunit g
  ATPase cation transporting 13A2
  ATPase phospholipid transporting 11C
  butyrophilin subfamily 2 member A2
  ceramide synthase 6
  cyclin and CBS domain divalent metal cation transport mediator 1
  diacylglycerol O-acyltransferase 1
  EBP cholestenol delta-isomerase
  ELOVL fatty acid elongase 2
  endoplasmic reticulum metallopeptidase 1
  family with sequence similarity 189 member B
  fat storage inducing transmembrane protein 2
  fatty acid desaturase 1
  frizzled class receptor 3
  frizzled class receptor 5
  G protein-coupled receptor 89A
  hydroxysteroid dehydrogenase like 1
  leucine rich repeat containing G protein-coupled receptor 4
  limb development membrane protein 1
  lysocardiolipin acyltransferase 1
  major facilitator superfamily domain containing 8
  membrane associated ring-CH-type finger 6
  membrane bound O-acyltransferase domain containing 7
  MIA SH3 domain ER export factor 2
  mitochondrially encoded ATP synthase 8
  NADH:ubiquinone oxidoreductase complex assembly factor 1
  OTU deubiquitinase 6A
  peptidyl-tRNA hydrolase 2
  phosphatidylinositol glycan anchor biosynthesis class N
  potassium inwardly rectifying channel subfamily J member 8
  protein O-mannose kinase
  protein tyrosine phosphatase non-receptor type 1
  reticulophagy regulator family member 3
  rhomboid domain containing 3
  SID1 transmembrane family member 2
  solute carrier family 12 member 4
  solute carrier family 12 member 6
  solute carrier family 12 member 7
  solute carrier family 12 member 9
  solute carrier family 15 member 4
  solute carrier family 19 member 2
  solute carrier family 4 member 2
  solute carrier family 47 member 1
  solute carrier family 6 member 6
  sphingosine-1-phosphate receptor 5
  suppression of tumorigenicity 7
  tetraspanin 3
  thioredoxin domain containing 15
  TLC domain containing 4
  transcription elongation factor A1
  translocase of outer mitochondrial membrane 34
  transmembrane protein 120B
  transmembrane protein 164
  transmembrane protein 179B
  transmembrane protein 184B
  transmembrane protein 259
  transmembrane protein 63B
  ubiquitin B
  vezatin, adherens junctions transmembrane protein
  zinc finger DHHC-type palmitoyltransferase 5
  zinc finger DHHC-type palmitoyltransferase 9
  zinc metallopeptidase STE24

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.