GUCY1A1, guanylate cyclase 1 soluble subunit alpha 1

GUCY1A1, guanylate cyclase 1 soluble subunit alpha 1

• Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

• Gene Synonyms (guanylate cyclase soluble subunit alpha-1, guanylate cyclase 1, soluble, alpha 3, soluble guanylate cyclase large subunit, GC-S-alpha-1, GC-SA3, GCS-alpha-3, GUC1A3, GUCA3, GUCSA3, GUCY1A3, MYMY6,)
• NCBI Gene ID: 2982
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q02108
  UNIPROT ID#>>B3KU69
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

guanylate cyclase 1 soluble subunit alpha 1 interacts with:

• ankyrin repeat and MYND domain containing 2
  ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
  COP9 signalosome subunit 4
  COP9 signalosome subunit 5
  guanylate cyclase 1 soluble subunit beta 1
  heterogeneous nuclear ribonucleoprotein L
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
  mitogen-activated protein kinase 8
  STIP1 homology and U-box containing protein 1
  tumor protein p53

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.