NDST1, N-deacetylase and N-sulfotransferase 1

NDST1, N-deacetylase and N-sulfotransferase 1

• This gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that resides in the Golgi apparatus. The encoded protein catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate to nitrogen of glucosamine in heparan sulfate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

• Gene Synonyms (bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1, HSNST 1, N-Deacetylase-N-sulfotransferase 1, N-HSST 1, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1, N-deacetylase/N-sulfotransferase 1, N-heparan sulfate sulfotransferase 1, NDST-1, [Heparan sulfate]-glucosamine N-sulfotransferase 1, glucosaminyl N-deacetylase/N-sulfotransferase 1, heparan sulfate-N-deacetylase/N-sulfotransferase, heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase 1, HSST, MRT46, NST1,)
• NCBI Gene ID: 3340
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B7Z1Q0
  UNIPROT ID#>>A8K8T3
  UNIPROT ID#>>E7EVJ3
  UNIPROT ID#>>P52848
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

N-deacetylase and N-sulfotransferase 1 interacts with:

• breast cancer 1, early onset
  CD83 molecule
  cytoplasmic polyadenylation element binding protein 4
  iduronate 2-sulfatase
  N-acylethanolamine acid amidase
  negative regulator of reactive oxygen species
  plasminogen activator, urokinase receptor
  SID1 transmembrane family, member 2
  tafazzin
  transmembrane protein 132A
  tumor protein p63
  vir like m6A methyltransferase associated
  X-ray repair cross complementing 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.