- Gene Overview
- Interaction Network
- Sequence Verification
MACC1, MET transcriptional regulator MACC1
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MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009]
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Gene Synonyms (7A5, SH3BP4L, metastasis-associated in colon cancer protein 1, MACC1, MET transcriptional regulator, SH3 domain-containing protein 7a5, metastasis associated in colon cancer 1, putative binding protein 7a5,)
- NCBI Gene ID:
346389
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q6ZN28
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
MET transcriptional regulator MACC1 interacts with:
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