LSS, lanosterol synthase

LSS, lanosterol synthase

• The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009]

• Gene Synonyms (APMR4, CTRCT44, HYPT14, OSC, lanosterol synthase, 2,3-epoxysqualene-lanosterol cyclase, epididymis secretory sperm binding protein, hOSC, lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase), oxidosqualene--lanosterol cyclase,)
• NCBI Gene ID: 4047
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P48449
  UNIPROT ID#>>B2R694
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

lanosterol synthase interacts with:

• calcium and integrin binding 1
  exportin 1
  factor interacting with PAPOLA and CPSF1
  glutamine amidotransferase like class 1 domain containing 1
  kinesin light chain 2
  limb development membrane protein 1 like
  LY6/PLAUR domain containing 4
  myosin heavy chain 9
  myosin VC
  neurotrophic receptor tyrosine kinase 1
  phosphatidylethanolamine binding protein 1
  PNKD metallo-beta-lactamase domain containing
  proteasome 26S subunit, non-ATPase 14
  ring finger protein 4
  solute carrier family 10 member 1
  solute carrier family 10 member 6
  TNF receptor superfamily member 10a
  transmembrane protein 167B
  transmembrane protein 86B
  Yip1 interacting factor homolog A, membrane trafficking protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.