MYH8, myosin heavy chain 8

MYH8, myosin heavy chain 8

• Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is predominantly expressed in fetal skeletal muscle. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in trismus-pseudocamptodactyly syndrome. [provided by RefSeq, Sep 2009]

• Gene Synonyms (DA7, MyHC-peri, MyHC-pn, gtMHC-F, myosin-8, fetal-myosin heavy chain, myHC-perinatal, myosin heavy chain, skeletal muscle, perinatal, myosin, heavy chain 8, skeletal muscle, perinatal, myosin, heavy polypeptide 8, skeletal muscle, perinatal,)
• NCBI Gene ID: 4626
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P13535
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

myosin heavy chain 8 interacts with:

• agrin
  aurora kinase C
  H4 clustered histone 1
  myosin heavy chain 13
  rogdi atypical leucine zipper
  TLE family member 3, transcriptional corepressor
  tropomyosin 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.