NELL2, neural EGFL like 2

NELL2, neural EGFL like 2

• The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains. The encoded protein acts as a homotrimer and is found in the cytoplasm. Several variants encoding a few different isoforms exist, and at least one isoform appears to be a secreted protein. Studies in mouse suggest that this protein plays a role in neural cell growth and differentiation as well as in oncogenesis. [provided by RefSeq, Feb 2009]

• Gene Synonyms (NRP2, protein kinase C-binding protein NELL2, NEL-like protein 2, NEL-related protein 2, neural epidermal growth factor-like 2,)
• NCBI Gene ID: 4753
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R0X1
  UNIPROT ID#>>B7Z625
  UNIPROT ID#>>Q99435
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

neural EGFL like 2 interacts with:

• ataxin 7
  ATP synthase inhibitory factor subunit 1
  centrosomal protein 44
  chromosome 4 open reading frame 48
  collectin subfamily member 11
  coronin 1A
  CST telomere replication complex component 1
  EGF like domain multiple 7
  elastin microfibril interfacer 2
  growth factor independent 1B transcriptional repressor
  kinesin family member 18B
  latent transforming growth factor beta binding protein 4
  paired box 3
  peroxidasin
  POC1 centriolar protein A
  POC1 centriolar protein B
  protein kinase cAMP-dependent type I regulatory subunit alpha
  ring finger protein 40
  RNA polymerase mitochondrial
  SEH1 like nucleoporin
  TNF receptor associated factor 7
  tRNA-yW synthesizing protein 3 homolog
  vir like m6A methyltransferase associated
  ZFP41 zinc finger protein
  zinc finger and BTB domain containing 40
  zinc finger and BTB domain containing 9
  zinc finger protein 101
  zinc finger protein 136
  zinc finger protein 408
  zinc finger protein 627

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.