NKX3-1, NK3 homeobox 1

NKX3-1, NK3 homeobox 1

• This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jan 2012]

• Gene Synonyms (BAPX2, NKX3, NKX3.1, NKX3A, homeobox protein Nkx-3.1, NK homeobox, family 3, A, NK3 transcription factor homolog A, NK3 transcription factor related, locus 1, homeobox protein NK-3 homolog A,)
• NCBI Gene ID: 4824
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q99801
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

NK3 homeobox 1 interacts with:

• apoptosis enhancing nuclease
  CD200 receptor 1 like
  centromere protein X
  chaperonin containing TCP1 subunit 7
  chondroitin polymerizing factor
  cytoskeleton associated protein 4
  DNA topoisomerase I
  family with sequence similarity 136 member A
  fem-1 homolog B
  heat shock protein 90 beta family member 1
  heterogeneous nuclear ribonucleoprotein A0
  high mobility group 20B
  homeodomain interacting protein kinase 2
  LIM and cysteine rich domains 1
  lysine acetyltransferase 2B
  parathymosin
  phosphatidylethanolamine binding protein 1
  RAB, member RAS oncogene family like 6
  retinoic acid receptor gamma
  Rhox homeobox family member 2
  ribosomal protein L37a
  ring finger protein 4
  SAM pointed domain containing ETS transcription factor
  serum response factor
  solute carrier family 22 member 18
  Sp1 transcription factor
  Sp2 transcription factor
  Sp3 transcription factor
  Sp4 transcription factor
  Sp5 transcription factor
  stathmin 3
  testis expressed 264, ER-phagy receptor
  TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase
  tumor protein, translationally-controlled 1
  WD repeat domain 77
  zinc finger protein 417

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.