TBC1D25, TBC1 domain family member 25

TBC1D25, TBC1 domain family member 25

• This gene encodes a protein with a TBC domain and functions as a Rab GTPase activating protein. The encoded protein is involved in the fusion of autophagosomes with endosomes and lysosomes. This gene was previously known as ornithine aminotransferase-like 1, but has no similarity to ornithine aminotransferase. [provided by RefSeq, Jan 2017]

• Gene Synonyms (MG81, OATL1, TBC1 domain family member 25, 5SN3 snoRNA, ornithine aminotransferase-like 1,)
• NCBI Gene ID: 4943
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DF03
  UNIPROT ID#>>Q3MII6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TBC1 domain family member 25 interacts with:

• ankyrin repeat domain 34A
  ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
  chibby family member 1, beta catenin antagonist
  cyclin dependent kinase 16
  DENN domain containing 1A
  doublecortin like kinase 1
  eukaryotic translation initiation factor 4E family member 2
  family with sequence similarity 110 member A
  family with sequence similarity 110 member B
  family with sequence similarity 53 member C
  family with sequence similarity 9 member B
  fasciculation and elongation protein zeta 1
  fasciculation and elongation protein zeta 2
  GABA type A receptor associated protein like 1
  GABA type A receptor associated protein like 2
  GABA type A receptor-associated protein
  galectin 14
  GRB10 interacting GYF protein 1
  GRB2 associated binding protein 2
  kinase suppressor of ras 1
  kinesin family member 13B
  La ribonucleoprotein 1B
  lamin tail domain containing 2
  leucine rich repeat and fibronectin type III domain containing 1
  LIM domain and actin binding 1
  MAPK associated protein 1
  membrane associated guanylate kinase, WW and PDZ domain containing 1
  microtubule associated protein 1 light chain 3 alpha
  microtubule associated protein 1 light chain 3 beta
  microtubule associated protein 1 light chain 3 gamma
  OMA1 zinc metallopeptidase
  potassium voltage-gated channel interacting protein 1
  protein phosphatase, Mg2+/Mn2+ dependent 1H
  RAB2A, member RAS oncogene family
  RAB3A interacting protein
  RUN and SH3 domain containing 1
  serine and arginine rich splicing factor 12
  SH3 and PX domains 2A
  SH3 domain binding protein 4
  signal induced proliferation associated 1 like 1
  SLIT-ROBO Rho GTPase activating protein 2
  synapse defective Rho GTPase homolog 1
  testis associated actin remodelling kinase 2
  tripartite motif family like 2
  ubiquitin specific peptidase 21
  zinc finger and BTB domain containing 21
  zinc finger protein 638

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.