FXYD3, FXYD domain containing ion transport regulator 3

FXYD3, FXYD domain containing ion transport regulator 3

• This gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]

• Gene Synonyms (FXYD domain-containing ion transport regulator 3, chloride conductance inducer protein Mat-8, mammary tumor 8 kDa protein, phospholemman-like protein, sodium/potassium-transporting ATPase subunit FXYD3, MAT8, PLML,)
• NCBI Gene ID: 5349
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14802
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

FXYD domain containing ion transport regulator 3 interacts with:

• anterior gradient 3, protein disulphide isomerase family member
  BCL2 like 13
  bestrophin 2
  cAMP responsive element binding protein 3
  cAMP responsive element binding protein 3 like 1
  EBP cholestenol delta-isomerase
  ERGIC and golgi 3
  ergosterol biosynthesis 28 homolog
  ETAA1 activator of ATR kinase
  family with sequence similarity 209 member A
  F-box and leucine rich repeat protein 12
  G protein-coupled receptor 152
  G protein-coupled receptor 37 like 1
  G protein-coupled receptor class C group 5 member D
  growth hormone inducible transmembrane protein
  KASH domain containing 5
  major facilitator superfamily domain containing 11
  major facilitator superfamily domain containing 5
  mitochondrial translational initiation factor 3
  mitogen-activated protein kinase 6
  nudix hydrolase 3
  phospholipid phosphatase 6
  SERPINE1 mRNA binding protein 1
  small transmembrane regulator of ion transport 1
  sodium voltage-gated channel beta subunit 3
  solute carrier family 1 member 1
  solute carrier family 10 member 1
  solute carrier family 10 member 6
  solute carrier family 16 member 12
  solute carrier family 18 member A1
  solute carrier family 30 member 2
  solute carrier family 35 member A1
  solute carrier family 35 member B1
  solute carrier family 35 member C2
  solute carrier family 39 member 2
  sphingolipid transporter 3 (putative)
  sphingosine-1-phosphate lyase 1
  syntaxin 3
  TLC domain containing 1
  translocase of inner mitochondrial membrane 23
  translocase of inner mitochondrial membrane domain containing 1
  translocator protein 2
  transmembrane BAX inhibitor motif containing 6
  transmembrane protein 179B
  transmembrane protein 52B
  transmembrane protein 80
  transmembrane protein 86A
  transmembrane protein 97
  XK related 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.