PTGER1, prostaglandin E receptor 1

PTGER1, prostaglandin E receptor 1

• The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. [provided by RefSeq, Jul 2008]

• Gene Synonyms (prostaglandin E2 receptor EP1 subtype, PGE receptor, EP1 subtype, PGE2 receptor EP1 subtype, prostaglandin E receptor 1 (subtype EP1), 42kD, prostaglandin E receptor 1 (subtype EP1), 42kDa, prostaglandin E receptor 1, subtype EP1, prostanoid EP1 receptor, EP1,)
• NCBI Gene ID: 5731
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P34995
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

prostaglandin E receptor 1 interacts with:

• prostaglandin E receptor 3
  prostaglandin E synthase
  prostaglandin F receptor
  prostaglandin-endoperoxide synthase 2
  ring finger protein 123

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.