RCN1, reticulocalbin 1

RCN1, reticulocalbin 1

• Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding. In human endothelial and prostate cancer cell lines this protein localizes to the plasma membrane.[provided by RefSeq, Jan 2009]

• Gene Synonyms (reticulocalbin-1, epididymis secretory protein Li 84, proliferation-inducing gene 20, reticulocalbin 1, EF-hand calcium binding domain, HEL-S-84, PIG20, RCAL, RCN,)
• NCBI Gene ID: 5954
• Species: Homo sapiens (Human)
• UNIPROT ID#>>V9HW95
  UNIPROT ID#>>Q15293
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

reticulocalbin 1 interacts with:

• AAR2 splicing factor
  ankyrin repeat and SOCS box containing 8
  apoptosis associated tyrosine kinase
  armadillo repeat containing 6
  assembly factor for spindle microtubules
  ataxin 1
  ATP synthase mitochondrial F1 complex assembly factor 2
  aurora kinase B
  autophagy and beclin 1 regulator 1
  Bet1 golgi vesicular membrane trafficking protein
  bone morphogenetic protein receptor, type 1A
  calreticulin 3
  cell division cycle and apoptosis regulator 1
  centromere protein E
  centrosomal protein 250
  centrosomal protein 76
  charged multivesicular body protein 4A
  chromobox 1
  chromosome 11 open reading frame 58
  coiled-coil domain containing 88A
  cullin 3
  cullin 7
  damage specific DNA binding protein 1
  DDB1 and CUL4 associated factor 11
  dual specificity phosphatase 19
  dual specificity phosphatase 21
  dual specificity tyrosine phosphorylation regulated kinase 4
  EF-hand domain containing 1
  EF-hand domain family member D2
  enkurin domain containing 1
  expressed sequence AI837181
  ezrin
  family with sequence similarity 110 member A
  F-box and leucine rich repeat protein 12
  G protein subunit beta 1 like
  G2 and S-phase expressed 1
  GDP-L-fucose synthase
  glutaredoxin 3
  growth arrest and DNA damage inducible gamma
  guanine monophosphate synthase
  HAUS augmin like complex subunit 2
  HAUS augmin-like complex, subunit 4
  heat shock protein 90 beta family member 1
  heat shock protein family A (Hsp70) member 4 like
  heterogeneous nuclear ribonucleoprotein L like
  histone deacetylase 11
  homeodomain interacting protein kinase 4
  importin 9
  insulin receptor substrate 4
  integrin alpha FG-GAP repeat containing 1
  lebercilin LCA5
  leucine rich repeat and fibronectin type III domain containing 1
  LIM domain only 3
  LIM domain only 4
  LTV1 ribosome biogenesis factor
  MAD2 mitotic arrest deficient-like 1
  MAD2 mitotic arrest deficient-like 2
  matrin 3
  matrix Gla protein
  methyltransferase like 22
  minichromosome maintenance complex component 3
  myosin XVB
  myosin XVIIIA
  nascent polypeptide associated complex subunit alpha 2
  NDC80 kinetochore complex component
  N-deacetylase and N-sulfotransferase 2
  nuclear RNA export factor 1
  OFD1 centriole and centriolar satellite protein
  peptidylprolyl isomerase like 3
  peptidyl-tRNA hydrolase 1 homolog
  potassium channel tetramerisation domain containing 5
  proprotein convertase subtilisin/kexin type 9
  prostaglandin E synthase 3
  protein phosphatase 1 regulatory subunit 9A
  protein tyrosine phosphatase non-receptor type 22
  RAB9A, member RAS oncogene family
  RAD18 E3 ubiquitin protein ligase
  radixin
  ribophorin II
  ribosomal RNA processing 1 homolog B (S. cerevisiae)
  ring finger protein 2
  ring finger protein 41
  ring-box 1
  RPGRIP1 like
  Sec23 homolog A, COPII coat complex component
  slingshot protein phosphatase 1
  small glutamine rich tetratricopeptide repeat containing alpha
  small glutamine rich tetratricopeptide repeat containing beta
  sperm antigen with calponin homology and coiled-coil domains 1 like
  SSX family member 2 interacting protein
  sulfiredoxin 1
  sulfotransferase family 1A member 1
  SUZ12 polycomb repressive complex 2 subunit
  target of myb1 like 2 membrane trafficking protein
  tectonic family member 1
  tectonic family member 3
  testin LIM domain protein
  trans-golgi network protein 2
  tripartite motif containing 14
  tripartite motif-containing 28
  tubulin alpha 1b
  tubulin alpha 1c
  ubiquitin fold modifier 1
  valosin containing protein
  vir like m6A methyltransferase associated
  von Willebrand factor A domain containing 1
  WD repeat domain 45B
  X-ray repair cross complementing 3
  zinc finger protein 410
  ZW10 interacting kinetochore protein
  zyxin

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.