RGS13, regulator of G protein signaling 13

RGS13, regulator of G protein signaling 13

• The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist. [provided by RefSeq, Jul 2008]

• Gene Synonyms (regulator of G-protein signaling 13, regulator of G-protein signalling 13,)
• NCBI Gene ID: 6003
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O14921
  UNIPROT ID#>>A0A024R989
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

regulator of G protein signaling 13 interacts with:

• apolipoprotein L6
  cytosolic iron-sulfur assembly component 1
  lin-9 DREAM MuvB core complex component
  metadherin
  serrate, RNA effector molecule
  signaling lymphocytic activation molecule family member 1

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