SPINK2, serine peptidase inhibitor Kazal type 2

SPINK2, serine peptidase inhibitor Kazal type 2

• This gene encodes a member of the family of serine protease inhibitors of the Kazal type (SPINK). The encoded protein acts as a trypsin and acrosin inhibitor in the genital tract and is localized in the spermatozoa. The protein has been associated with the progression of lymphomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

• Gene Synonyms (serine protease inhibitor Kazal-type 2, epididymis tissue protein Li 172, serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor), HUSI-II, SPGF29,)
• NCBI Gene ID: 6691
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024RD95
  UNIPROT ID#>>P20155
  UNIPROT ID#>>D6RC51
  UNIPROT ID#>>D6RI10
  UNIPROT ID#>>A0A087WTA9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

serine peptidase inhibitor Kazal type 2 interacts with:

• ADAMTS like 4
  ATPase H+ transporting V1 subunit D
  CTTNBP2 N-terminal like
  DDB1 and CUL4 associated factor 15
  distal membrane arm assembly complex 2 like
  IKBKB interacting protein
  keratin associated protein 10-3
  mitogen-activated protein kinase 8 interacting protein 2
  MOB family member 4, phocein
  notch 2 N-terminal like A
  nudix hydrolase 8
  peptidase, mitochondrial processing subunit alpha
  peptidase, mitochondrial processing subunit beta
  phosphoribosyl transferase domain containing 1
  pyruvate dehyrogenase phosphatase catalytic subunit 2
  ring finger and SPRY domain containing 1
  striatin
  striatin 3
  striatin 4
  striatin interacting protein 1
  ubiquitin protein ligase E3 component n-recognin 1
  ubiquitin protein ligase E3 component n-recognin 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.