CLRN1, clarin 1

CLRN1, clarin 1

• This gene encodes a protein that contains a cytosolic N-terminus, multiple helical transmembrane domains, and an endoplasmic reticulum membrane retention signal, TKGH, in the C-terminus. The encoded protein may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIIa. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (clarin-1, Usher syndrome type-3 protein, RP61, USH3, USH3A,)
• NCBI Gene ID: 7401
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P58418
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

clarin 1 interacts with:

• ALG8 alpha-1,3-glucosyltransferase
  BRICHOS domain containing 5
  C2CD2 like
  calcium activated nucleotidase 1
  C-C motif chemokine ligand 4 like 2
  claudin 19
  cortexin 3
  DNA damage regulated autophagy modulator 1
  family with sequence similarity 24 member B
  fucosyltransferase 9
  major facilitator superfamily domain containing 5
  nurim
  SEC22 homolog B, vesicle trafficking protein
  solute carrier family 34 member 3
  transmembrane inner ear
  transmembrane protein 140
  transmembrane protein 147
  transmembrane protein 222
  transmembrane protein 239
  transmembrane protein 31
  transmembrane protein 86B
  transmembrane protein with metallophosphoesterase domain
  transmembrane serine protease 4
  unc-50 inner nuclear membrane RNA binding protein
  zinc finger DHHC-type palmitoyltransferase 15

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.