WNT6, Wnt family member 6

WNT6, Wnt family member 6

• The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level. [provided by RefSeq, Jul 2008]

• Gene Synonyms (protein Wnt-6, wingless-type MMTV integration site family, member 6,)
• NCBI Gene ID: 7475
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8N2E5
  UNIPROT ID#>>Q9Y6F9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Wnt family member 6 interacts with:

• porcupine O-acyltransferase
  ras homolog family member U

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.