SSPN, sarcospan

SSPN, sarcospan

• This gene encodes a member of the dystrophin-glycoprotein complex (DGC). The DGC spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Two alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]

• Gene Synonyms (sarcospan, K-ras oncogene-associated protein, Kras oncogene-associated, kirsten-ras-associated protein, microspan, nanospan, sarcospan (Kras oncogene-associated gene), DAGA5, KRAG, NSPN, SPN1, SPN2,)
• NCBI Gene ID: 8082
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14714
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

sarcospan interacts with:

• SPT6, histone chaperone and transcription elongation factor

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.