ACOX2, acyl-CoA oxidase 2

ACOX2, acyl-CoA oxidase 2

• The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe cognitive disability, and death in children. [provided by RefSeq, Mar 2009]

• Gene Synonyms (peroxisomal acyl-coenzyme A oxidase 2, 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase, 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase, THCA-CoA oxidase, acyl-CoA oxidase 2, branched chain, acyl-Coenzyme A oxidase 2, branched chain, branched chain acyl-CoA oxidase, peroxisomal branched chain acyl-CoA oxidase, trihydroxycoprostanoyl-CoA oxidase, BCOX, BRCACOX, BRCOX, CBAS6, THCCox,)
• NCBI Gene ID: 8309
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q99424
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

acyl-CoA oxidase 2 interacts with:

• striatin 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.