KREMEN1, kringle containing transmembrane protein 1

KREMEN1, kringle containing transmembrane protein 1

• This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (kremen protein 1, dickkopf receptor, kringle domain-containing transmembrane protein 1, kringle-coding gene marking the eye and the nose, kringle-containing protein marking the eye and the nose, ECTD13, KREMEN, KRM1,)
• NCBI Gene ID: 83999
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96MU8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

kringle containing transmembrane protein 1 interacts with:

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