RAX2, retina and anterior neural fold homeobox 2

RAX2, retina and anterior neural fold homeobox 2

• This gene encodes a homeodomain-containing protein that plays a role in eye development. Mutation of this gene causes age-related macular degeneration type 6, an eye disorder resulting in accumulations of protein and lipid beneath the retinal pigment epithelium and within the Bruch's membrane. Defects in this gene can also cause cone-rod dystrophy type 11, a disease characterized by the initial degeneration of cone photoreceptor cells and resulting in loss of color vision and visual acuity, followed by the degeneration of rod photoreceptor cells, which progresses to night blindness and the loss of peripheral vision. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

• Gene Synonyms (retina and anterior neural fold homeobox protein 2, Q50-type retinal homeobox protein, retina and anterior neural fold homeobox like 1, retina and anterior neural fold homeobox-like protein 1, ARMD6, CORD11, QRX, RAXL1,)
• NCBI Gene ID: 84839
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96IS3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

retina and anterior neural fold homeobox 2 interacts with:

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.