IDI2, isopentenyl-diphosphate delta isomerase 2

IDI2, isopentenyl-diphosphate delta isomerase 2

• The protein encoded by this gene catalyzes the conversion of isopentenyl diphosphate to dimethylallyl diphosphate, which is a precursor for the synthesis of cholesterol and other isoprenoids. This gene, which is a product of an ancestral gene duplication event, encodes a protein that may be involved in the aggregation of alpha-synuclein in the cerebral cortex of patients with Lewy body disease. In addition, segmental copy number gains in this locus have been associated with sporadic amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2016]

• Gene Synonyms (isopentenyl-diphosphate delta-isomerase 2, IPP isomerase 2, diphosphate dimethylallyl diphosphate isomerase 2, isopentenyl pyrophosphate isomerase 2, isopentenyl-diphosphate Delta-isomerase 2, IPPI2,)
• NCBI Gene ID: 91734
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BXS1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

isopentenyl-diphosphate delta isomerase 2 interacts with:

• family with sequence similarity 76 member B
  single stranded DNA binding protein 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.