CTLA-4 Blockade Bioassay Propagation Model Technical Manual
Instructions for Use of Product(s)
JA1400
Literature # TM517
The CTLA-4 Blockade Bioassay, Propagation Model, is a bioluminescent cell-based assay that overcomes the limitations of existing assays and can be used to measure the potency and stability of antibodies and other biologics targeting CTLA-4.
Summary of Changes
The following changes were made to the 5/25 revision of this document:
1. In Section 7.B, two instances of "aAPC/Raji Effector Cells" were changed to "aAPC/Raji Cells".
2. A third party trademark was updated.
3. Miscellaneous text edits were made.
Revised 5/25.