NAMPT, nicotinamide phosphoribosyltransferase

NAMPT, nicotinamide phosphoribosyltransferase

• This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10. [provided by RefSeq, Feb 2011]

• Gene Synonyms (nicotinamide phosphoribosyltransferase, NAmPRTase, pre-B cell-enhancing factor, pre-B-cell colony-enhancing factor 1, 1110035O14Rik, PBEF, PBEF1, VF, VISFATIN,)
• NCBI Gene ID: 10135
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P43490
  UNIPROT ID#>>A0A024R718
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nicotinamide phosphoribosyltransferase interacts with:

• AAR2 splicing factor
  anterior gradient 2, protein disulphide isomerase family member
  chromosome 16 open reading frame 71
  DET1 and DDB1 associated 1
  egl-9 family hypoxia inducible factor 3
  F-box and WD repeat domain containing 11
  interferon induced transmembrane protein 3
  LEO1 homolog, Paf1/RNA polymerase II complex component
  mitogen-activated protein kinase 15
  nicotinamide phosphoribosyltransferase
  nicotinate phosphoribosyltransferase
  N-myc downstream regulated 1
  nuclear RNA export factor 1
  pleckstrin homology domain containing A4
  RIO kinase 1
  testin LIM domain protein
  transmembrane protein 25
  tripartite motif containing 28
  U2 small nuclear RNA auxiliary factor 2
  ubiquitin specific peptidase 49
  WD repeat domain 77

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.