SIRPB1, signal regulatory protein beta 1

SIRPB1, signal regulatory protein beta 1

• The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

• Gene Synonyms (CD172b, SIRP-BETA-1, signal-regulatory protein beta-1, CD172 antigen-like family member B,)
• NCBI Gene ID: 10326
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5TFQ8
  UNIPROT ID#>>O00241
  UNIPROT ID#>>H9KV29
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

signal regulatory protein beta 1 interacts with:

• BPI fold containing family A member 1
  RNA binding fox-1 homolog 1
  RNA binding protein, mRNA processing factor
  signal regulatory protein beta 1

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