EHD1, EH domain containing 1

EHD1, EH domain containing 1

• This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The protein encoded by this gene is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]

• Gene Synonyms (H-PAST, HPAST1, PAST, PAST1, EH domain-containing protein 1, PAST homolog 1, testilin,)
• NCBI Gene ID: 10938
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B2R5U3
  UNIPROT ID#>>A0A024R571
  UNIPROT ID#>>Q9H4M9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

EH domain containing 1 interacts with:

• aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
  ankyrin repeat and FYVE domain containing 1
  arginyltransferase 1
  chromosome 19 open reading frame 54
  CTP synthase 2
  cyclin L2
  EH domain binding protein 1
  EH domain containing 1
  EH domain containing 3
  EH domain containing 4
  EH-domain containing 3
  epsin 1
  epsin 3
  exocyst complex component 8
  family with sequence similarity 153 member B
  family with sequence similarity 98 member B
  FKBP prolyl isomerase 9
  MICAL like 1
  microtubule associated monooxygenase, calponin and LIM domain containing 1
  mitochondrial E3 ubiquitin protein ligase 1
  NAD(P)HX epimerase
  phosphodiesterase 12
  pleckstrin homology domain containing A4
  programmed cell death 10
  RAB11 family interacting protein 2
  rabenosyn, RAB effector
  ring finger and FYVE like domain containing E3 ubiquitin protein ligase
  serine/threonine kinase 39
  SNW domain containing 1
  SPANX family member N3
  syntaxin 12
  TERF1 interacting nuclear factor 2
  terminal nucleotidyltransferase 4B
  thioredoxin related transmembrane protein 1
  translocase of outer mitochondrial membrane 22
  transmembrane protein 25
  ubiquitin like modifier activating enzyme 6
  WD repeat and FYVE domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.