ECI1, enoyl-CoA delta isomerase 1

ECI1, enoyl-CoA delta isomerase 1

• This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010]

• Gene Synonyms (enoyl-CoA delta isomerase 1, mitochondrial, 3,2 trans-enoyl-Coenzyme A isomerase, 3,2-trans-enoyl-CoA isomerase, mitochondrial, D3,D2-enoyl-CoA isomerase, acetylene-allene isomerase, delta(3),Delta(2)-enoyl-CoA isomerase, dodecenoyl-CoA delta isomerase (3,2 trans-enoyl-CoA isomerase), dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase), epididymis secretory sperm binding protein, DCI,)
• NCBI Gene ID: 1632
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P42126
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

enoyl-CoA delta isomerase 1 interacts with:

• 3-hydroxy-3-methylglutaryl-CoA synthase 1
  3-hydroxyisobutyryl-CoA hydrolase
  acid phosphatase 6, lysophosphatidic
  anterior gradient 2, protein disulphide isomerase family member
  chitinase domain containing 1
  clusterin associated protein 1
  cutA divalent cation tolerance homolog
  dihydrolipoamide dehydrogenase
  dual specificity phosphatase 10
  enoyl-CoA hydratase, short chain 1
  fatty acid binding protein 5
  glutathione-disulfide reductase
  heat shock protein family D (Hsp60) member 1
  HtrA serine peptidase 2
  malate dehydrogenase 1
  MAPK associated protein 1
  mitochondrial ribosomal protein L58
  NFU1 iron-sulfur cluster scaffold
  ornithine aminotransferase
  peroxiredoxin 6
  phosphogluconate dehydrogenase
  pleckstrin homology domain containing A4
  protection of telomeres 1
  RAB9A, member RAS oncogene family
  RNA exonuclease 2
  serine/threonine kinase receptor associated protein
  superoxide dismutase 2
  TNFAIP3 interacting protein 2
  transferrin
  transgelin 2
  tripartite motif containing 25
  tyrosine kinase 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.