SEPTIN1, septin 1

SEPTIN1, septin 1

• This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012]

• Gene Synonyms (septin-1, differentiation 6 (deoxyguanosine triphosphate triphosphohydrolase), peanut-like protein 3, serologically defined breast cancer antigen NY-BR-24, DIFF6, LARP, PNUTL3, SEP1, SEPT1,)
• NCBI Gene ID: 1731
• Species: Homo sapiens (Human)
• UNIPROT ID#>>J3KNL2
  UNIPROT ID#>>Q8WYJ6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

septin 1 interacts with:

• angiomotin
  ankyrin repeat and SOCS box containing 7
  aurora kinase B
  DNA damage inducible transcript 4 like
  DnaJ heat shock protein family (Hsp40) member B13
  G protein signaling modulator 1
  golgi reassembly stacking protein 2
  heat shock transcription factor 2 binding protein
  ligand of numb-protein X 1
  midline 2
  mitochondrial ribosomal protein L12
  myosin XVIIIA
  nardilysin convertase
  NGG1 interacting factor 3 like 1
  PIH1 domain containing 1
  protein interacting with PRKCA 1
  RAD21 cohesin complex component
  receptor interacting serine/threonine kinase 4
  septin 1
  septin 10
  septin 11
  septin 12
  septin 2
  septin 3
  septin 4
  septin 5
  septin 6
  septin 8
  septin 9
  syndecan binding protein
  testis expressed 11
  toll interacting protein
  ubiquitin C
  ubiquitin conjugating enzyme E2 I

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.