EGR2, early growth response 2

EGR2, early growth response 2

• The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

• Gene Synonyms (AT591, CHN1, CMT1D, CMT4E, KROX20, E3 SUMO-protein ligase EGR2, E3 SUMO-protein transferase ERG2, KROX-20, Drosophila, homolog (early growth response-2), early growth response protein 2, zinc finger protein Krox-20,)
• NCBI Gene ID: 1959
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P11161
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

early growth response 2 interacts with:

• DNA methyltransferase 3 like
  golgin A2
  host cell factor C1
  Jupiter microtubule associated homolog 2
  mediator complex subunit 31
  microspherule protein 1
  NADH:ubiquinone oxidoreductase core subunit S2
  NGFI-A binding protein 2
  nuclear factor of activated T cells 1
  phosphodiesterase 4D interacting protein
  ribosomal modification protein rimK like family member B
  ribosomal protein L7 like 1
  RNA binding motif protein 15B
  snail family transcriptional repressor 1
  SRY-box transcription factor 10
  SRY-box transcription factor 8
  steroid receptor RNA activator 1
  ubiquitin conjugating enzyme E2 I
  WW domain containing E3 ubiquitin protein ligase 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.