FLOT2, flotillin 2

FLOT2, flotillin 2

• Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ECS-1, ECS1, ESA, ESA1, M17S1, flotillin-2, Flotillin 2 (epidermal surface antigen 1), epidermal surface antigen, membrane component chromosome 17 surface marker 1, membrane component, chromosome 17, surface marker 1 (35kD protein identified by monoclonal antibody ECS-1),)
• NCBI Gene ID: 2319
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BTI6
  UNIPROT ID#>>A0A024QZ62
  UNIPROT ID#>>Q6FG43
  UNIPROT ID#>>Q14254
  UNIPROT ID#>>J3QLD9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

flotillin 2 interacts with:

• actin, beta
  AKT serine/threonine kinase 3
  ATP binding cassette subfamily B member 6 (Langereis blood group)
  ATP binding cassette subfamily E member 1
  ATPase H+ transporting accessory protein 2
  Bet1 golgi vesicular membrane trafficking protein
  bone morphogenetic protein receptor, type 1A
  caveolae associated protein 1
  CD2-associated protein
  centriolar coiled-coil protein 110
  charged multivesicular body protein 4B
  charged multivesicular body protein 4B
  chromobox 1
  coiled-coil domain containing 8
  complement component 1, q subcomponent binding protein
  coronin, actin binding protein 1C
  cullin 7
  cyclic GMP-AMP synthase
  delta 4-desaturase, sphingolipid 1
  DISC1 scaffold protein
  Ecm29 proteasome adaptor and scaffold
  embryonic ectoderm development
  ER lipid raft associated 2
  fibronectin 1
  filamin, beta
  flotillin 1
  flotillin 1
  FYN proto-oncogene, Src family tyrosine kinase
  G protein subunit gamma 12
  golgi reassembly stacking protein 2
  golgi transport 1B
  hepatocyte growth factor-regulated tyrosine kinase substrate
  heterogeneous nuclear ribonucleoprotein U like 2
  integrin alpha FG-GAP repeat containing 1
  KRAS proto-oncogene, GTPase
  ligand of numb-protein X 1
  LIM domain and actin binding 1
  lysosomal associated membrane protein 1
  MAGE family member B4
  membrane magnesium transporter 1
  membrane metalloendopeptidase
  membrane spanning 4-domains A4A
  mitochondrial antiviral signaling protein
  mitochondrial pyruvate carrier 2
  mitochondrial ribosomal protein S14
  moesin
  myelin expression factor 2
  myelin protein zero like 3
  myosin VI
  myosin XIX
  myosin, heavy polypeptide 10, non-muscle
  nicotinamide nucleotide adenylyltransferase 1
  ninein
  obscurin like cytoskeletal adaptor 1
  peptidylprolyl isomerase E
  peptidyl-tRNA hydrolase 2
  pleckstrin homology domain containing A4
  protein tyrosine phosphatase non-receptor type 1
  protein tyrosine phosphatase, non-receptor type 23
  RAB2A, member RAS oncogene family
  RAB5C, member RAS oncogene family
  RAB5C, member RAS oncogene family
  RAB7A, member RAS oncogene family
  regulator of microtubule dynamics 3
  ribosomal protein S6 kinase A1
  ribosomal protein S6 kinase A2
  ribosomal protein S6 kinase A6
  ring finger protein 4
  signal sequence receptor subunit 1
  small glutamine rich tetratricopeptide repeat containing beta
  solute carrier family 26 member 6
  spastin
  spermatogenesis associated 24
  sterol O-acyltransferase 1
  supervillin
  synaptopodin
  TAR DNA binding protein
  TBC1 domain family member 15
  TNFAIP3 interacting protein 2
  trafficking from ER to golgi regulator
  transcription factor CP2
  trans-golgi network protein 2
  translocase of outer mitochondrial membrane 40
  transmembrane p24 trafficking protein 2
  transmembrane protein 17
  transmembrane protein 185A
  transmembrane protein 63B
  transmembrane protein 79
  tripartite motif-containing 69
  tropomodulin 3
  tumor susceptibility gene 101
  U2 small nuclear RNA auxiliary factor 2
  ubiquinol-cytochrome c reductase complex assembly factor 3
  ubiquitin C
  ubiquitin conjugating enzyme E2 A
  ubiquitin specific peptidase 14
  vacuolar protein sorting 28
  vacuolar protein sorting 4B
  VAMP associated protein A
  vesicle associated membrane protein 2
  voltage dependent anion channel 1
  voltage dependent anion channel 2
  Yes1 associated transcriptional regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.