GAP43, growth associated protein 43

GAP43, growth associated protein 43

• The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (B-50, GAP-43, PP46, neuromodulin, axonal membrane protein GAP-43, calmodulin-binding protein P-57, nerve growth-related peptide GAP43, neural phosphoprotein B-50, neuron growth-associated protein 43, protein F1,)
• NCBI Gene ID: 2596
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5U058
  UNIPROT ID#>>P17677
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

growth associated protein 43 interacts with:

• caseinolytic mitochondrial matrix peptidase proteolytic subunit
  cullin 4B
  cyclin L2
  cytochrome P450 family 2 subfamily S member 1
  gap junction protein beta 7
  glycerophosphodiester phosphodiesterase 1
  kinesin associated protein 3
  lactate dehydrogenase B
  MARVEL domain containing 2
  mediator complex subunit 21
  ornithine aminotransferase
  phosphoenolpyruvate carboxykinase 2, mitochondrial
  phospholipase C delta 1
  protein kinase C beta
  protein kinase C delta
  protocadherin gamma subfamily C, 3
  rabaptin, RAB GTPase binding effector protein 1
  serine hydroxymethyltransferase 2
  solute carrier family 25 member 41
  spectrin alpha, non-erythrocytic 1
  sphingosine-1-phosphate receptor 2
  tigger transposable element derived 5
  transmembrane protein 185A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.