GRIK1, glutamate ionotropic receptor kainate type subunit 1

GRIK1, glutamate ionotropic receptor kainate type subunit 1

• Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to alter the properties of ion flow. Alternative splicing, resulting in transcript variants encoding different isoforms, has been noted for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (glutamate receptor ionotropic, kainate 1, excitatory amino acid receptor 3, glutamate receptor 5, EAA3, EEA3, GLR5, GLUR5, GluK1, gluR-5,)
• NCBI Gene ID: 2897
• Species: Homo sapiens (Human)
• UNIPROT ID#>>E7ENK3
  UNIPROT ID#>>P39086
  UNIPROT ID#>>E9PD61
  UNIPROT ID#>>B7Z256
  UNIPROT ID#>>E7EPY9
  UNIPROT ID#>>E7EPZ0
  UNIPROT ID#>>B7Z3V7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

glutamate ionotropic receptor kainate type subunit 1 interacts with:

• glutamate ionotropic receptor kainate type subunit 1
  glutamate receptor interacting protein 1
  heterogeneous nuclear ribonucleoprotein L
  homer scaffold protein 1
  obscurin like cytoskeletal adaptor 1
  protein interacting with PRKCA 1
  syndecan binding protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.