HELLS, helicase, lymphoid specific

HELLS, helicase, lymphoid specific

• This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2014]

• Gene Synonyms (lymphoid-specific helicase, SWI/SNF2-related, matrix-associated, actin-dependent regulator of chromatin, subfamily A, member 6, proliferation-associated SNF2-like protein, ICF4, LSH, Nbla10143, PASG, SMARCA6,)
• NCBI Gene ID: 3070
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q76H82
  UNIPROT ID#>>Q0VGL2
  UNIPROT ID#>>Q9NRZ9
  UNIPROT ID#>>A0A0B4J1V9
  UNIPROT ID#>>F6XU50
  UNIPROT ID#>>A0A087WSW7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

helicase, lymphoid specific interacts with:

• cell division cycle 14B
  chromobox 4
  coiled-coil domain containing 8
  developmental pluripotency-associated 3
  elongation factor Tu GTP binding domain containing 2
  ER membrane protein complex subunit 2
  fibrillarin
  forkhead box A3
  forkhead box Q1
  gametocyte specific factor 1 like
  GCN1 activator of EIF2AK4
  H2B clustered histone 8
  H3 clustered histone 1
  H4 clustered histone 1
  heat shock protein family A (Hsp70) member 5
  limb development membrane protein 1 like
  LY6/PLAUR domain containing 3
  lysosomal associated membrane protein 2
  mesenchyme homeobox 2
  mindbomb E3 ubiquitin protein ligase 1
  MYC proto-oncogene, bHLH transcription factor
  NEDD1 gamma-tubulin ring complex targeting factor
  neurotrophic receptor tyrosine kinase 1
  platelet derived growth factor receptor beta
  pleckstrin homology domain containing A4
  protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
  PVR cell adhesion molecule
  pyrimidinergic receptor P2Y6
  receptor interacting serine/threonine kinase 4
  RNA polymerase II associated protein 2
  RNA polymerase II associated protein 3
  SERTA domain containing 2
  SNW domain containing 1
  solute carrier family 25 member 1
  solute carrier family 39 member 9
  staufen double-stranded RNA binding protein 1
  structural maintenance of chromosomes 1A
  SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
  TEA domain transcription factor 2
  tektin 2
  transmembrane protein 150A
  transmembrane protein 171
  tripartite motif containing 25
  ubiquitin specific peptidase 47
  valosin containing protein
  VAMP associated protein A
  WD repeat domain 5
  WD repeat domain 76

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.