HSPE1, heat shock protein family E (Hsp10) member 1

HSPE1, heat shock protein family E (Hsp10) member 1

• This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011]

• Gene Synonyms (10 kDa heat shock protein, mitochondrial, 10 kDa chaperonin, chaperonin 10, early-pregnancy factor, epididymis secretory sperm binding protein, heat shock 10kD protein 1 (chaperonin 10), heat shock 10kDa protein 1, CPN10, EPF, GROES, HSP10,)
• NCBI Gene ID: 3336
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P61604
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

heat shock protein family E (Hsp10) member 1 interacts with:

• AAR2 splicing factor
  activator of HSP90 ATPase activity 1
  aldehyde dehydrogenase 6 family member A1
  apoptosis inducing factor mitochondria associated 1
  ataxin 3
  ATP binding cassette subfamily E member 1
  autophagy related 16 like 1
  caseinolytic mitochondrial matrix peptidase chaperone subunit X
  chaperonin containing TCP1 subunit 2
  chaperonin containing TCP1 subunit 3
  chaperonin containing TCP1 subunit 4
  chaperonin containing TCP1 subunit 5
  charged multivesicular body protein 4A
  chromobox 3
  coenzyme Q2, polyprenyltransferase
  creatine kinase, mitochondrial 1A
  destrin, actin depolymerizing factor
  dual serine/threonine and tyrosine protein kinase
  ergosterol biosynthesis 28 homolog
  ezrin
  FAD dependent oxidoreductase domain containing 1
  glutathione S-transferase omega 1
  glyoxylate and hydroxypyruvate reductase
  heat shock protein family A (Hsp70) member 4 like
  heat shock protein family H (Hsp110) member 1
  HEXIM P-TEFb complex subunit 1
  inositol monophosphatase 2
  integrin subunit alpha 4
  isocitrate dehydrogenase (NADP(+)) 1
  La ribonucleoprotein 7, transcriptional regulator
  ligand dependent nuclear receptor interacting factor 1
  LIM and SH3 protein 1
  mannose phosphate isomerase
  methionine sulfoxide reductase A
  methyltransferase like 14
  mitogen-activated protein kinase kinase 7
  moesin
  N-terminal glutamine amidase 1
  parathymosin
  peptidase D
  peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  peptidylprolyl isomerase A
  peptidylprolyl isomerase B
  peptidylprolyl isomerase F
  phosphatidylethanolamine binding protein 1
  phosphoenolpyruvate carboxykinase 2, mitochondrial
  phosphoethanolamine/phosphocholine phosphatase 1
  phosphoglucomutase 2 like 1
  phosphoglucomutase 5
  phosphoglycerate dehydrogenase
  phosphoglycerate kinase 2
  phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
  pirin
  plastin 3
  pyridoxamine 5'-phosphate oxidase
  quinoid dihydropteridine reductase
  radixin
  RB binding protein 7, chromatin remodeling factor
  RE1 silencing transcription factor
  regucalcin
  reticulocalbin 1
  selenoprotein M
  sepiapterin reductase
  serine hydroxymethyltransferase 1
  serine hydroxymethyltransferase 2
  serine/threonine kinase 3
  spermidine/spermine N1-acetyltransferase 1
  sterol O-acyltransferase 1
  stress induced phosphoprotein 1
  striatin 3
  superoxide dismutase 1
  superoxide dismutase 2
  thimet oligopeptidase 1
  thioredoxin
  TLE family member 1, transcriptional corepressor
  TNFAIP3 interacting protein 2
  transaldolase 1
  transgelin
  transgelin 2
  transgelin 3
  transketolase
  triosephosphate isomerase 1
  tRNA methyltransferase 61B
  U2 small nuclear RNA auxiliary factor 2
  ubiquitin conjugating enzyme E2 L3
  ubiquitin conjugating enzyme E2 M
  ubiquitin fold modifier 1
  ubiquitin like modifier activating enzyme 5
  UDP-glucose pyrophosphorylase 2
  unc-119 lipid binding chaperone
  unk zinc finger
  valosin containing protein
  vascular cell adhesion molecule 1
  vir like m6A methyltransferase associated
  WD repeat domain 1
  zinc fingers and homeoboxes 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.