HTR6, 5-hydroxytryptamine receptor 6

HTR6, 5-hydroxytryptamine receptor 6

• This gene encodes a protein that belongs to the seven-transmembrane G protein-coupled receptor family of proteins. The encoded protein couples with the Gs alpha subunit and stimulates adenylate cyclase to activate the cyclic AMP-dependent signaling pathway. This receptor is thought to regulate cholinergic neuronal transmission in the brain. Several antidepressants and antipsychotic drugs have a high affinity for this receptor. [provided by RefSeq, Aug 2013]

• Gene Synonyms (5-hydroxytryptamine receptor 6, 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled, serotonin receptor 6, 5-HT6, 5-HT6R,)
• NCBI Gene ID: 3362
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P50406
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

5-hydroxytryptamine receptor 6 interacts with:

• ataxin 10
  component of oligomeric golgi complex 3
  COP9 signalosome subunit 5
  COPI coat complex subunit gamma 2
  cullin associated and neddylation dissociated 2 (putative)
  exocyst complex component 2
  exportin 4
  exportin for tRNA
  importin 8
  microtubule associated protein 1B
  N-ethylmaleimide sensitive factor, vesicle fusing ATPase
  neurochondrin
  neurofibromin 1
  non-SMC condensin I complex subunit G
  RAN binding protein 6
  regulatory associated protein of MTOR complex 1
  SMG1 nonsense mediated mRNA decay associated PI3K related kinase
  TELO2 interacting protein 1
  telomere maintenance 2
  transportin 1
  tubulin folding cofactor D

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.