KCNH2, potassium voltage-gated channel subfamily H member 2

KCNH2, potassium voltage-gated channel subfamily H member 2

• This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ERG-1, ERG1, H-ERG, HERG, HERG1, Kv11.1, LQT2, SQT1, potassium voltage-gated channel subfamily H member 2, eag homolog, eag-related protein 1, ether-a-go-go-related gene potassium channel 1, ether-a-go-go-related potassium channel protein, ether-a-go-go-related protein 1, human ether-a-go-go-related, long QT syndrome type 2, potassium channel, voltage gated eag related subfamily H, member 2, potassium voltage-gated channel, subfamily H (eag-related), member 2, voltage-gated potassium channel subunit Kv11.1,)
• NCBI Gene ID: 3757
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q15BH2
  UNIPROT ID#>>Q12809
  UNIPROT ID#>>A0A090N8Q0
  UNIPROT ID#>>A0A090N7X5
  UNIPROT ID#>>A0A090N7W1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

potassium voltage-gated channel subfamily H member 2 interacts with:

• ALG10 alpha-1,2-glucosyltransferase
  ALG10 alpha-1,2-glucosyltransferase B
  BAG cochaperone 2
  cell division cycle 73
  cullin 1
  FERM domain containing 8
  FKBP prolyl isomerase 8
  NADH:ubiquinone oxidoreductase subunit S6
  NEDD4 like E3 ubiquitin protein ligase
  neurotrophic receptor tyrosine kinase 1
  potassium voltage-gated channel subfamily E regulatory subunit 2
  potassium voltage-gated channel subfamily H member 2
  protein kinase cAMP-activated catalytic subunit alpha
  RAB11A, member RAS oncogene family
  ring finger and FYVE like domain containing E3 ubiquitin protein ligase
  ring finger protein 139
  ring finger protein 207
  sigma non-opioid intracellular receptor 1
  STIP1 homology and U-box containing protein 1
  stress induced phosphoprotein 1
  TRIO and F-actin binding protein
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.