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LIMS1, LIM zinc finger domain containing 1

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LIMS1, LIM zinc finger domain containing 1

  • The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

  • Gene Synonyms (PINCH, PINCH-1, PINCH1, LIM and senescent cell antigen-like-containing domain protein 1, LIM and senescent cell antigen-like domains 1, LIM-type zinc finger domains 1, particularly interesting new Cys-His protein 1, renal carcinoma antigen NY-REN-48, senescent cell antigen,)
  • NCBI Gene ID: 3987
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>P48059
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

LIM zinc finger domain containing 1 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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