MAK, male germ cell associated kinase

MAK, male germ cell associated kinase

• The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. Mutations in this gene have been associated with ciliary defects resulting in retinitis pigmentosa 62. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

• Gene Synonyms (RP62, serine/threonine-protein kinase MAK, male germ cell-associated kinase retinal-enriched isoform, serine/threonine protein kinase MAK, testicular secretory protein Li 28,)
• NCBI Gene ID: 4117
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A140VK28
  UNIPROT ID#>>F8VBW7
  UNIPROT ID#>>P20794
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

male germ cell associated kinase interacts with:

• anaphase promoting complex subunit 11
  ciliogenesis associated kinase 1
  cyclin dependent kinase 20
  F-box protein 7
  fizzy and cell division cycle 20 related 1
  HEXIM P-TEFb complex subunit 1
  katanin interacting protein
  La ribonucleoprotein 7, transcriptional regulator
  male germ cell associated kinase
  NADH:ubiquinone oxidoreductase subunit B7
  nectin cell adhesion molecule 3
  peroxiredoxin 2
  protein phosphatase 2 catalytic subunit beta
  serine incorporator 1
  SLAM family member 7
  staphylococcal nuclease and tudor domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.