NFIL3, nuclear factor, interleukin 3 regulated

NFIL3, nuclear factor, interleukin 3 regulated

• The protein encoded by this gene is a transcriptional regulator that binds as a homodimer to activating transcription factor (ATF) sites in many cellular and viral promoters. The encoded protein represses PER1 and PER2 expression and therefore plays a role in the regulation of circadian rhythm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Feb 2014]

• Gene Synonyms (E4BP4, IL3BP1, NF-IL3A, NFIL3A, nuclear factor interleukin-3-regulated protein, E4 promoter-binding protein 4, adenovirus E4 promoter region binding protein, interleukin-3 promoter transcriptional activator, interleukin-3-binding protein 1, transcriptional activator NF-IL3A,)
• NCBI Gene ID: 4783
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R241
  UNIPROT ID#>>Q16649
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nuclear factor, interleukin 3 regulated interacts with:

• angiomotin like 2
  basic leucine zipper ATF-like transcription factor
  cAMP responsive element binding protein 3
  chromobox 8
  COP1 E3 ubiquitin ligase
  DNA methyltransferase 3 like
  germ cell-less 1, spermatogenesis associated
  H4 clustered histone 1
  heat shock transcription factor 2 binding protein
  MAF bZIP transcription factor F
  minichromosome maintenance 9 homologous recombination repair factor
  nuclear factor, interleukin 3 regulated
  origin recognition complex subunit 1
  phosphodiesterase 9A
  PIH1 domain containing 2
  RAD50 interactor 1
  serine/threonine kinase 40
  TNF receptor associated factor 2
  tumor protein p63
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.