NGFR, nerve growth factor receptor

NGFR, nerve growth factor receptor

• Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR, tumor necrosis factor receptor superfamily member 16, NGF receptor, TNFR superfamily, member 16, low affinity neurotrophin receptor p75NTR, low-affinity nerve growth factor receptor, p75 ICD,)
• NCBI Gene ID: 4804
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P08138
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nerve growth factor receptor interacts with:

• bifunctional apoptosis regulator
  brain expressed X-linked 1
  brain expressed X-linked 3
  fascin actin-bundling protein 1
  kinase D interacting substrate 220
  leucine rich repeat and Ig domain containing 1
  MAGE family member D1
  MAGE family member H1
  mitogen-activated protein kinase 1
  mitogen-activated protein kinase 3
  nerve growth factor receptor
  neurotrophic receptor tyrosine kinase 1
  neurotrophic receptor tyrosine kinase 2
  neurotrophic receptor tyrosine kinase 3
  neurotrophin 4
  NSE3 homolog, SMC5-SMC6 complex component
  PDZ and LIM domain 1
  protein kinase cAMP-activated catalytic subunit beta
  protein tyrosine phosphatase non-receptor type 13
  receptor interacting serine/threonine kinase 2
  reticulon 4 receptor
  ribophorin II
  sequestosome 1
  SHC adaptor protein 1
  siah E3 ubiquitin protein ligase 1
  sortilin 1
  stathmin 2
  survival of motor neuron 1, telomeric
  thymidine kinase 1
  TNF receptor associated factor 1
  TNF receptor associated factor 2
  TNF receptor associated factor 3
  TNF receptor associated factor 4
  TNF receptor associated factor 5
  TNF receptor associated factor 6
  TNFRSF1A associated via death domain
  transcription factor 19
  transformer 2 beta homolog
  transthyretin
  tumor protein p53
  ubiquitin recognition factor in ER associated degradation 1
  zinc finger protein 274

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.