OXCT1, 3-oxoacid CoA-transferase 1

OXCT1, 3-oxoacid CoA-transferase 1

• This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency. [provided by RefSeq, Jul 2008]

• Gene Synonyms (OXCT, SCOT, succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial, 3-oxoacid CoA transferase, SCOT-s, epididymis secretory sperm binding protein, somatic-type succinyl-CoA:3-oxoacid CoA-transferase, succinyl CoA:3-oxoacid CoA transferase, succinyl-CoA:3-ketoacid-CoA transferase,)
• NCBI Gene ID: 5019
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P55809
  UNIPROT ID#>>A0A024R040
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

3-oxoacid CoA-transferase 1 interacts with:

• 3-oxoacid CoA-transferase 1
  3-oxoacid CoA-transferase 2
  AHNAK nucleoprotein
  aminoadipate aminotransferase
  apoptosis inducing factor mitochondria associated 1
  BCL2 like 14
  chromobox 3
  chromosome 11 open reading frame 58
  coiled-coil-helix-coiled-coil-helix domain containing 4
  cytidine/uridine monophosphate kinase 1
  formation of mitochondrial complex V assembly factor 1 homolog
  GrpE like 1, mitochondrial
  IQ motif containing B1
  kynurenine aminotransferase 3
  lysophospholipase 1
  mitochondrial rRNA methyltransferase 1
  MYG1 exonuclease
  myotrophin
  N-sulfoglucosamine sulfohydrolase
  p21 (RAC1) activated kinase 5
  parathymosin
  peroxiredoxin 6
  phosphogluconate dehydrogenase
  phosphoglycerate kinase 1
  plasmanylethanolamine desaturase 1
  plasminogen activator, urokinase receptor
  pleckstrin homology domain containing A4
  presenilin 1
  proteasome activator subunit 1
  protein tyrosine phosphatase mitochondrial 1
  protein tyrosine phosphatase non-receptor type 11
  pyruvate dehydrogenase kinase 1
  RB binding protein 7, chromatin remodeling factor
  ribonucleic acid export 1
  S100 calcium binding protein A16
  septin 11
  serine protease 35
  SH3 domain binding glutamate rich protein like 3
  SR-related CTD associated factor 4
  succinate dehydrogenase complex assembly factor 2
  succinate dehydrogenase complex flavoprotein subunit A
  succinate-CoA ligase ADP-forming subunit beta
  succinate-CoA ligase GDP/ADP-forming subunit alpha
  succinate-CoA ligase GDP-forming subunit beta
  superoxide dismutase 1
  supervillin
  syntaxin binding protein 1
  thimet oligopeptidase 1
  thioredoxin reductase 2
  TNF receptor associated protein 1
  torsin 1A interacting protein 1
  transaldolase 1
  transferrin
  translocase of inner mitochondrial membrane 9
  transmembrane protein 177
  transmembrane protein 9
  treacle ribosome biogenesis factor 1
  triosephosphate isomerase 1
  tripartite motif containing 28
  tRNA methyltransferase 61B
  tyrosine kinase 2
  tyrosyl-tRNA synthetase 2
  ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
  ubiquitin C-terminal hydrolase L1
  UBX domain protein 7
  vacuolar ATPase assembly factor VMA21
  VAMP associated protein B and C
  WD repeat domain 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.