HOOK1, hook microtubule tethering protein 1

HOOK1, hook microtubule tethering protein 1

• This gene encodes a member of the hook family of coiled-coil proteins, which bind to microtubules and organelles through their N- and C-terminal domains, respectively. The encoded protein localizes to discrete punctuate subcellular structures, and interacts with several members of the Rab GTPase family involved in endocytosis. It is thought to link endocytic membrane trafficking to the microtubule cytoskeleton. Several alternatively spliced transcript variants have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

• Gene Synonyms (protein Hook homolog 1, h-hook1, hHK1, hook homolog 1, HK1,)
• NCBI Gene ID: 51361
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UJC3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

hook microtubule tethering protein 1 interacts with:

• ADP ribosylation factor GTPase activating protein 2
  AKT interacting protein
  alanyl-tRNA synthetase domain containing 1
  ankyrin repeat domain 23
  APC membrane recruitment protein 1
  arachidonate lipoxygenase 3
  autophagy and beclin 1 regulator 1
  BRCA2 and CDKN1A interacting protein
  centrosomal protein 192
  chromosome 6 open reading frame 141
  coiled-coil and C2 domain containing 1A
  CWF19 like cell cycle control factor 2
  DEAH-box helicase 37
  eukaryotic translation initiation factor 4E nuclear import factor 1
  FAM161 centrosomal protein A
  family with sequence similarity 160 member A1
  family with sequence similarity 160 member A2
  family with sequence similarity 160 member B1
  family with sequence similarity 160 member B2
  family with sequence similarity 91 member A1
  G-patch domain containing 1
  HAUS augmin like complex subunit 1
  HAUS augmin like complex subunit 3
  HAUS augmin like complex subunit 4
  hook microtubule tethering protein 1
  hook microtubule tethering protein 3
  intraflagellar transport 20
  intraflagellar transport 22
  intraflagellar transport 46
  intraflagellar transport 74
  KIAA1671
  kinesin light chain 2
  kinesin light chain 4
  KRI1 homolog
  LDL receptor related protein 1B
  leukocyte receptor cluster member 8
  limb development membrane protein 1 like
  methylcrotonoyl-CoA carboxylase 1
  methylcrotonoyl-CoA carboxylase 2
  mitochondrial poly(A) polymerase
  myocardin related transcription factor B
  NEDD4 binding protein 2
  nucleoporin 43
  pleckstrin homology domain containing A4
  protein phosphatase 6 regulatory subunit 3
  rabenosyn, RAB effector
  RIMS binding protein 3
  ring finger protein 31
  signal induced proliferation associated 1 like 2
  SNW domain containing 1
  SUFU negative regulator of hedgehog signaling
  synaptonemal complex central element protein 1
  tetratricopeptide repeat domain 26
  trafficking kinesin protein 2
  ubiquitin protein ligase E3 component n-recognin 5
  ubiquitin specific peptidase 47
  ubiquitin specific peptidase 54
  vacuolar protein sorting 13 homolog C
  VPS16 core subunit of CORVET and HOPS complexes
  VPS18 core subunit of CORVET and HOPS complexes
  WASH complex subunit 2A
  WD repeat domain 62
  zinc finger and BTB domain containing 47
  zinc finger protein 250
  zinc finger protein 326
  zinc finger protein 572
  zinc finger protein 655
  zinc finger protein 764
  zinc finger protein 785

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.