PIK3R2, phosphoinositide-3-kinase regulatory subunit 2

PIK3R2, phosphoinositide-3-kinase regulatory subunit 2

• Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Three transcript variants, one protein coding and the other two non-protein coding, have been found for this gene. [provided by RefSeq, Apr 2019]

• Gene Synonyms (phosphatidylinositol 3-kinase regulatory subunit beta, PI3-kinase subunit p85-beta, PI3K regulatory subunit beta, phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta), phosphoinositide-3-kinase regulatory subunit beta, phosphoinositide-3-kinase, regulatory subunit 2 (beta), ptdIns-3-kinase regulatory subunit p85-beta, MPPH, MPPH1, P85B, p85, p85-BETA,)
• NCBI Gene ID: 5296
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O00459
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphoinositide-3-kinase regulatory subunit 2 interacts with:

• adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
  amine oxidase copper containing 3
  bromodomain containing 7
  coronin 1C
  cullin 3
  DPY30 domain containing 1
  egl-9 family hypoxia inducible factor 3
  enkurin, TRPC channel interacting protein
  F-box and leucine rich repeat protein 2
  fibronectin leucine rich transmembrane protein 1
  GRB2 associated binding protein 2
  HAUS augmin like complex subunit 1
  HAUS augmin like complex subunit 4
  HEPACAM family member 2
  hepatitis A virus cellular receptor 2
  IKAROS family zinc finger 3
  insulin receptor substrate 2
  insulin receptor substrate 4
  IQ motif containing GTPase activating protein 1
  keratin 20
  keratin 38
  keratin 6C
  keratin 79
  MANSC domain containing 1
  matrix metallopeptidase 25
  mediator complex subunit 28
  Morf4 family associated protein 1 like 1
  myelin basic protein
  myosin heavy chain 14
  nuclear RNA export factor 1
  phosphatase and tensin homolog
  phosphoinositide-3-kinase regulatory subunit 3
  prostaglandin E receptor 3
  protein tyrosine phosphatase non-receptor type 11
  RAD50 interactor 1
  ribosomal protein S10
  ribosomal protein S5
  ribosomal protein S6 kinase A2
  ribosomal protein S7
  ring finger protein 144A
  ring finger protein 19B
  semenogelin 1
  semenogelin 2
  sequestosome 1
  SHC adaptor protein 1
  signal transducer and activator of transcription 3
  SOS Ras/Rac guanine nucleotide exchange factor 1
  spectrin beta, non-erythrocytic 1
  spleen associated tyrosine kinase
  src kinase associated phosphoprotein 1
  stabilin 1
  suppressor of cytokine signaling 1
  suppressor of cytokine signaling 6
  suppressor of cytokine signaling 7
  tec protein tyrosine kinase
  transforming growth factor beta receptor 1
  transforming growth factor beta receptor 2
  transmembrane protein 52B
  tubulin alpha 1c
  tubulin beta 6 class V
  tubulin beta class I
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  valosin containing protein
  vascular cell adhesion molecule 1
  V-set and immunoglobulin domain containing 4
  WASP family member 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.